MOLECULAR GENETICS

It is a genetic analysis method that can detect a single nucleotide change in the DNA sequence consisting of 3.2 billion nucleotides that make up our hereditary code. Only 1.5% of DNA consists of protein-coding regions, and the resulting proteins ensure the normal course of life. The smallest functional part of DNA responsible for a particular trait is a gene. With this method, the genes that may cause the suspected disease are examined and the molecular etiology of the disease is tried to be clarified. More than 10,000 diseases can be diagnosed, also known as single gene diseases or mendelian diseases. A single gene analysis can be done or all genes responsible for the disease can be evaluated as a panel study. In addition, thanks to advances in genetic technologies, all protein-coding regions (approximately 20 thousand genes) in an individual´s DNA can be examined without a specific pre-diagnosis, and the success of diagnosis can be increased.

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